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Invited Talks:
Invited Talks:
Arc Institute Symposium | 2025
Arc Institute Symposium | 2025
Title: De Novo Design of Biased Analogs for Adipose-Centric Weight Loss
Presented structure-guided engineering of biased analogs to selectively drive adipose tissue remodeling, highlighting translational cytokine design strategies.
Keystone Symposia | 2022
Keystone Symposia | 2022
Title: IL-27 Modulates Macrophage Metabolism During HSV-1 Infection to Regulate Immunopathology
Selected oral presentation. Recipient of Keystone Travel Award. Demonstrated IL-27–mediated control of macrophage immunometabolism to enhance antiviral immunity while limiting inflammatory pathology in vivo. Abstract
Chicago Ophthalmology – Advances in Vision Sciences (COAVS) | 2022
Chicago Ophthalmology – Advances in Vision Sciences (COAVS) | 2022
Title: Role of IL-27 in HSV-1–Mediated Keratitis and Encephalitis
Invited seminar on regulatory cytokine control of antiviral immunity and neuroinflammatory pathology.
Association for Research in Vision and Ophthalmology (ARVO) | 2021
Association for Research in Vision and Ophthalmology (ARVO) | 2021
Title: IL-27 Regulates Corneal Immunopathology and Viral Clearance During HSV-1 Infection
Recipient of ARVO Travel Grant. Identified IL-27–dependent enhancement of type I interferon responses and viral clearance during stromal keratitis. Abstract
Publications:
2024
2024
Antony, F., Kinha, D., Nowinska, A., Rouse, B. T., & Suryawanshi, A.
The immunobiology of corneal HSV-1 infection and herpetic stromal keratitis. Clinical Microbiology Reviews, e00006-24. View Publication
2023
2023
Antony, F., Pundkar, C., Sandey, M., & Suryawanshi, A.
Role of IL-27 in HSV-1–Induced Herpetic Stromal Keratitis. The Journal of Immunology. View Publication
Antony, F., Kang, X., ... & Suryawanshi, A.
Targeting β-catenin using XAV939 nanoparticle promotes immunogenic cell death and suppresses conjunctival melanoma progression. International Journal of Pharmaceutics, 640, 123043. View Publication
Pundkar, C., Antony, F., ... & Suryawanshi, A.
Targeting Wnt/β-catenin signaling using XAV939 nanoparticles in tumor microenvironment-conditioned macrophages to promote immunogenicity. Heliyon. View Publication
Ren, J., Antony, F., Rouse, B. T., & Suryawanshi, A.
Role of Innate Interferon Responses at the Ocular Surface in Herpes Simplex Virus-1–Induced Herpetic Stromal Keratitis. Pathogens, 12(3), 437. View Publication
2021
2021
Antony, F., Pundkar, C., ... & Suryawanshi, A.
IFN-λ Regulates Neutrophil Biology to Suppress Inflammation in Herpes Simplex Virus-1–Induced Corneal Immunopathology. The Journal of Immunology, 206(8), 1866–1877.View Publication
2020
2020
Antony, F., Vashi, Y., Morla, S., Mohan, H., & Kumar, S.
Therapeutic potential of Nitazoxanide against Newcastle disease virus: a possible modulation of host cytokines. Cytokine, 131, 155115. View Publication
2019
2019
Saikia, J., Pandey, G., Sasidharan, S., Antony, F., ... & Ramakrishnan, V.
Electric field disruption of amyloid aggregation: potential noninvasive therapy for Alzheimer’s disease. ACS Chemical Neuroscience, 10(5), 2250–2262. View Publication
PhD Research Highlight
PhD Research Highlight
Herpes Stromal Keratitis (HSK), caused by HSV-1, is a leading cause of infectious blindness.
My work explores immune mechanisms driving HSK and identifies potential therapeutic strategies. We discovered that interleukin-27 (IL-27) plays a dual role—enhancing antiviral responses, regulating CD4+ T cells, and limiting corneal inflammation. HSV-1 also manipulates macrophage metabolism, promoting itaconate production that suppresses type-I interferon and IL-27 responses. These findings suggest that targeting the itaconate/IL-27 pathway could provide a novel approach to treat HSK and prevent vision loss. View thesis
Poster Sessions
Poster Sessions
AAI Immunology | 2023
AAI Immunology | 2023
β-Catenin Inhibition Using XAV939 Nanoparticle Promotes Immunogenic Cell Death and Suppresses Tumor Progression
Presented work on macrophage reprogramming and tumor immunogenicity. Abstract
BOSHELL Diabetes & Metabolic Disease Research Program – Research Day | 2021
BOSHELL Diabetes & Metabolic Disease Research Program – Research Day | 2021
Metabolic Reprogramming of Macrophages by Interleukin-27 During Herpes Simplex Virus-1 (HSV) Infection
Second place poster award. Demonstrated that IL-27 signaling regulates macrophage glycolysis and inflammation during HSV-induced stromal keratitis, suggesting a metabolic-targeted therapeutic approach.
Auburn University Research Symposium | 2020
Auburn University Research Symposium | 2020
IFN-λ Regulates Early Events in HSV-Induced Corneal Immunopathology
Best Poster Award. Characterized type I and III interferon responses during corneal HSV infection and showed how early IFN-λ treatment reduces inflammation and viral replication.
Indian Society of Immunology and Biotechnology | 2018
Indian Society of Immunology and Biotechnology | 2018
Inhibitory Effect of Nitazoxanide on Newcastle Disease Virus Infection: A Possible Repurposing of Drug
Best Poster Award. Presented work demonstrating the antiviral effects of Nitazoxanide and its potential for therapeutic repurposing.
Inhibitory Effect of Nitazoxanide on Newcastle Disease Virus Infection: A Possible Repurposing of Drug
Best Poster Award. Presented work demonstrating the antiviral effects of Nitazoxanide and its potential for therapeutic repurposing.
Selected Institutional Seminars:
Drug Discovery & Development Seminar | 2023
Harrison College of Pharmacy, Auburn University
Title: β-Catenin Inhibition Using XAV939 Nanoparticles Promotes Macrophage Immunogenicity and Suppresses Conjunctival Melanoma
Auburn University Student Research Symposium | 2021
Auburn University Student Research Symposium | 2021
Title: IL-27 Regulates Corneal Immunopathology and Viral Clearance During HSV-1 Infection
Phi Zeta Research Emphasis Day | 2022
Phi Zeta Research Emphasis Day | 2022
Auburn University
Title: β-Catenin Inhibition During Conjunctival Melanoma Suppresses Tumor Progression
Phi Zeta Research Emphasis Day | 2020
Phi Zeta Research Emphasis Day | 2020
Auburn University
Title: Interleukin-27 Regulates Corneal Immunopathology and Viral Clearance During HSV-1 Infection
Phi Zeta Research Emphasis Day | 2019
Phi Zeta Research Emphasis Day | 2019
Auburn University
Title: IFN-λ Regulates Early Events in HSV-1–Induced Corneal Immunopathology
Invited Peer Reviewer
Invited Peer Reviewer
I have been invited to serve as a peer reviewer for multiple peer-reviewed journals in immunology and biomedical research, reflecting recognition of my expertise in cytokine biology, host–pathogen interactions, and immunometabolism. In this role, I critically evaluate manuscripts for scientific rigor, experimental design, mechanistic depth, and translational relevance, contributing to the integrity and advancement of the scientific literature.
Invited reviewer for:
Frontiers in Immunology
Heliyon
PLOS ONE
The Ocular Surface
BMC Immunology
PeerJ- Life and Environment
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